Figure 1.

Detection of Dhcr24 expression in heart tissue. (A), The expression of Dhcr24 in the heart tissues from WT mice at 1, 3 and 6 mo of age was detected by Western blot. (B), Quantitative analysis of Dhcr24 in the WT mice used GAPDH for normalization (n = 3 mice per group). (C), Dhcr24 expression in heart tissues of the cTnT^{R 141W} transgenic mice at 3 mo of age was detected by Western blot. (D), Quantitative analysis of Dhcr24 in the cTnT^{R 141W} mice used GAPDH for normalization (n = 3 mice per group, **P < .01). (E), Immunodetection of Dhcr24 in the heart from the cTnT^{R 141W} and the NTG mice at 5 mo of age. Scale bar = 20 μm. (F), The cholesterol level in the heart tissues of the cTnT^{R 141W} and the NTG mice (n = 3 mice per group, **P < .01)