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. 2019 Jan 30;19:112. doi: 10.1186/s12885-019-5311-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Receiver operating characteristic (ROC) curves of miRNA detection and Pap test in identifying missed high-grade lesions from colposcopy-guided biopsy diagnosed LSIL/CIN1. a ROC curves of down-regulated miRNAs (miRNA195 and miRNA29a) (compared with consistent LSIL/CIN1 group); b ROC curves of up-regulated miRNAs (miRNA16–2 and miRNA20a) (compared with consistent LSIL/CIN1 group) LSIL/CIN1: Low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1