Table 1.
Characteristics of the study subjects
| Histology | P value | ||
|---|---|---|---|
| Consistent LSIL/CIN1 group (n = 150) | Missed high-grade lesion group (n = 27) | ||
| Age (years) | |||
| Mean (SD) | 39.4 (±6.6) | 39.8 (±7.1) | |
| < 40 | 68 (45.33%) | 12 (44.44%) | 0.932 |
| ≥ 40 | 82 (54.67%) | 15 (55.56%) | |
| HR-HPV | |||
| Positive | 130 (86.67%) | 27 (100%) | 0.044 |
| Negative | 20 (13.33%) | 0 (0%) | |
| HPV genotyping | |||
| Positive of HPV16,18 | 35 (23.33%) | 8 (29.63%) | 0.483 |
| Negative of HPV16,18 | 115 (76.67%) | 19 (70.37%) | |
| Pap test | |||
| ASC-H- | 137 (91.33%) | 21 (77.78%) | 0.036 |
| ASC-H+ | 13 (8.67%) | 6 (22.22%) | |
| Smoking | |||
| Non-smoker | 105 (70%) | 21 (77.78%) | 0.411 |
| Smoker* | 45 (30%) | 6 (22.22%) | |
| Number of lifetime sexual partners | |||
| 1 | 123 (82%) | 21 (77.78%) | 0.604 |
| 2+ | 27 (18%) | 6 (22.22%) | |
| Age at first sexual intercourse (years) | |||
| < 20 | 40 (26.67%) | 7 (25.93%) | 0.474 |
| 20–24 | 90 (60%) | 14 (51.85%) | |
| > 24 | 20 (13.33%) | 6 (22.22%) | |
The P value was calculated by the Pearson Chi-Square test
LSIL/CIN1: Low-grade squamous intraepithelial lesion/cervical intraepithelial neoplasia grade 1
SD Standard Deviation
HPV Human papillomavirus
HR-HPV High-risk human papillomavirus
ASC-H+ equal or greater than atypical squamous cells-cannot exclude high-grade squamous intraepithelial lesion
*including smokers and second-hand smoker subjects