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. 2019 Jan 30;20:21. doi: 10.1186/s12931-019-0976-3

Table 2.

Eating a high fat diet did not affect the number of pregnancies or time to confirmed pregnancy or initial pregnancy weight gain of female C57Bl/6 J mice

Outcome LFD HFD
First pregnancy
 Confirmed pregnancies (n) 14/14 14/14
 Time to confirmed pregnancy (days) 10.5 ± 0.8 10.9 ± 0.8
 Weight gain - first 10 days of pregnancy (g) 4.8 ± 0.5 5.2 ± 0.6
                  (%) 123 ± 3 122 ± 3
Second pregnancy
 Confirmed pregnancies (n) 8/14 8/14
 Time to confirmed pregnancy (days) 9.8 ± 0.4 8.4 ± 0.6
 Weight gain - first 10 days of pregnancy (g) 5.0 ± 0.6 5.3 ± 0.5
                  (%) 124 ± 3 122 ± 3

From 4 weeks of age, C57Bl/6 J female mice (n = 28) were separated into 2 treatment groups and fed either a low fat diet (LFD, n = 14) or high fat diet (HFD, n = 14). Female mice were first mated with C57Bl/6 J male mice after dams had been fed either diet for 12 weeks. Three weeks later, offspring were born. Dams were re-mated 1 week after their first litters were removed at 2 weeks of age. Data are shown as mean ± SEM