Table 5.

Dams exhibited signs of obesity when fed a high fat diet for 29 weeks

Outcome	LFD	HFD
Body weight (g)	26.1 ± 0.5	38.5 ± 1.8*
Body length (snout to vent) (mm)	88.9 ± 0.8	96.4 ± 0.7*
Body mass index (kg/m2)	3.30 ± 0.08	4.14 ± 0.18*
Gonadal white adipose tissue (g)	0.52 ± 0.10	3.84 ± 0.35*

*p < 0.05, compared with dams fed a LFD (student’s t test)

From 4 weeks of age, C57Bl/6 J female mice (n = 28) were separated into 2 treatment groups and fed either a low fat diet (LFD, n = 14) or high fat diet (HFD, n = 14) for 29 weeks. Female mice were mated with male C57Bl/6 J mice after dams were fed either diet for 12 weeks. Three weeks later, offspring were born. Dams were re-mated 1 week after their first litters were removed at 2 weeks of age. Data are shown as mean ± SEM for n = 13–14 dams/treatment