Table 1.
Correlations between LOXL4 expression and clinicopathologic parameters in patients with HCC
| Clinicopathological parameter | N | Expression of LOXL4 | p valueb | |
|---|---|---|---|---|
| Low (n = 89, %) | High (n = 165, %) | |||
| Age (years) | ||||
| < 50 | 120 | 45 (37.5) | 75 (62.5) | 0.259 |
| ≥ 50 | 134 | 44 (32.8) | 90 (67.2) | |
| Gender | ||||
| Female | 34 | 9 (26.5) | 25 (73.5) | 0.176 |
| Male | 220 | 80 (36.4) | 140 (63.6) | |
| Liver cirrhosis | ||||
| Yes | 201 | 68 (33.8) | 133 (66.2) | 0.264 |
| No | 53 | 21 (39.6) | 32 (60.4) | |
| Tumor size | ||||
| ≤ 5 cm | 124 | 49 (39.5) | 75 (60.5) | 0.092 |
| > 5 cm | 130 | 40 (30.8) | 90 (69.2) | |
| Tumor differentiation | ||||
| I | 3 | 3 (100.0) | 0 (0) | 0.003 |
| II | 72 | 31 (43.1) | 41 (56.9) | |
| III | 125 | 31 (24.8) | 94 (75.2) | |
| IV | 1 | 0 (0) | 1 (100.0) | |
| Vascular invasion | ||||
| Yes | 58 | 12 (20.7) | 46 (79.3) | 0.006 |
| No | 196 | 77 (39.3) | 119 (60.7) | |
| TNM stage | ||||
| I | 125 | 49 (39.2) | 76 (60.8) | 0.046 |
| II | 56 | 24 (42.9) | 32 (57.1) | |
| III | 64 | 15 (23.4) | 49 (76.6) | |
| IV | 8 | 1 (12.5) | 7 (87.5) | |
aThe bold number represents the p-values with significant differences
bP value was calculated by χ2 test or Fisher’s exact test