Table 5.
Comparison of models for prediction of CVD and CHD mortality without and with addition of electrocardiographic abnormalities
| ECG | CVD mortality | CHD mortality | ||||||
|---|---|---|---|---|---|---|---|---|
| abnormalities | Men n = 281 | Women n = 167 | Men n = 172 | Women n = 96 | ||||
| Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | |
| HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |||||
| No | – | 1 | – | 1 | – | 1 | – | 1 |
| Yes | – | 2.34 (1.72–3.19) | – | 1.56 (1.09–2.24) | – | 2.15 (1.44–3.22) | – | 1.71 (1.07–2.73) |
| Harrell‘s C | 0.704 | 0.730 | 0.803 | 0.814 | 0.715 | 0.745 | 0.829 | 0.842 |
| LRT (p-value) | – | 24.62 (< 0.001) | – | 5.48 (0.019) | – | 12.02 (< 0.001) | – | 4.79 (0.029) |
| IDI (p-value) | – | 0.013 (0.007) | – | 0.004 (0.040) | – | 0.010 (< 0.001) | – | 0.004 (0.173) |
| NRI (p-value) | – | 0.186 (0.007) | – | 0.186 (0.153) | – | 0.252 (0.027) | – | 0.212 (0.206) |
Model 1 – factors included into model: age, education, arterial hypertension, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglycerides, body mass index, smoking; Model 2 – variables of Model 1 plus ECG abnormalities
CHD coronary heart disease, CI confidence interval, CVD cardiovascular diseases, HR hazard ratio, IDI integrated discrimination improvement, LRT likelihood ratio test, NRI net reclassification index
Bold typeface indicates significance