Table 1.
Mean hearing thresholds in ABR test (ABR mean dB ± standard deviation)
Groups | Day 0 | Day 4 | Day 8 |
---|---|---|---|
Group I (Control Group) | 10.50±4.37 | 10.50±5.50 | 11.00±4.18 |
Group II (Cisplatin group) | 10.00±4.08 | 16.50±3.37a | 25.00±3.53ab |
Group III (Cisplatin + Cortexin group) | 9.50±4.97 | 13.50±3.37 | 16.00±2.23c |
The variables were expressed as mean±standard deviation.
Compared to the Control group, Cisplatin group had significantly elevated hearing thresholds on the 4th and the 8th days (p<0.05).
Cisplatin group had significantly elevated hearing threshold on the 8th day compared to the 4th day (p<0.05).
Comparison of the mean hearing thresholds of Cisplatin+Cortexin group and Cisplatin group on the 8th day indicated that there was a significant decrease in the Cisplatin+Cortexin group (p<0.05).
ABR: auditory brainstem response