Table 3.
Apoptotic index (%) | ||
---|---|---|
Day 4 | Day 8 | |
Group I (Control Group) | 0±0 | 0±0 |
Group II (Cisplatin group) | 4.16±0.40a | 9.50±0.83ab |
Group III (Cisplatin + Cortexin group) | 3.66±0.51a | 2.25 ± 0.50ac |
The variables were expressed as mean±standard deviation.
Compared to the control group, a significant level of apoptosis was present in Cisplatin and Cisplatin+Cortexin groups on the 4th and the 8th days of the study (p<0.05).
AI values recorded on the 8th day was significantly higher compared to the values on 4th day in Cisplatin group (p<0.05).
When Cisplatin+Cortexin and Cisplatin groups were compared for Day 8 values, a significant decrease was found in Cisplatin+Cortexin group (p<0.05)