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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: J Endocrinol. 2018 Jun 21;238(3):221–230. doi: 10.1530/JOE-18-0238

Figure 6.

Figure 6

Protein EIAs were used to determine whole-pituitary levels of the transcriptional factors PROP1 and Pou1f1 in control and Somatotrope LEPR null mice from 3 age groups. A Female mutants do not show any differences in PROP1 expression. B Male mutants show increased PROP1 expression at PND 4–5 (p<0.024) and PND 15 (p<0.001). C Females mutants have reduced expression of Pou1f1 at PND 8–10 (p<0.009) and PND 15 (p<0.024). D Pou1f1 is elevated in male mutants on PND8–10 (p<0.013). Values shown are mean ± SEM. Students t-test; PND 4–5: n=11–16, PND 8–10: n=10–18, PND 15: n= 6–11.