Table 1. Regulators of Nox5.
Stimulators | Inhibitors |
---|---|
Nox5-binding proteins/chaperone proteins | |
Calmodulin | Cav-1 |
Hsp90 | Hsp70 |
CHIP | |
Protein kinases | |
PKCα | PKCɛ |
CAM kinase II | |
ERK1/2 | |
c-Abl | |
c-Src | |
Transcription factors | |
NF-κB | |
AP-1 | |
STAT1/STAT3 |
AP-1, activator protein 1; CAM kinase II, Ca2+/calmodulin-dependent protein kinase II; ERK1/2, extracellular signal-regulated kinase1/2; NF-κB, nuclear factor κB; Nox, NADPH oxidase; PKC, protein kinase C; STAT, signal transducer and activator of transcription.