Table 5.
ROC analysis for clinical and laboratory findings of controls and A+B groups
Control–AB | AUC | SE | P-value | 95% CI | Cutoff | Sensitivity (%) | Specificity (%) |
---|---|---|---|---|---|---|---|
FEV1 (%) | 0.904 | 0.031 | ≤0.001 | 0.844–0.964 | 91.00 | 90.9 | 84.1 |
FEV1/FVC (%) | 1.000 | 0.000 | ≤0.001 | 1.000–1.000 | 73.00 | 100 | 100 |
CRP (mg/L) | 0.414 | 0.056 | 0.161 | 0.303–0.525 | 0.23 | 60.6 | 42.0 |
NF-κB (ng/mL) | 0.330 | 0.053 | 0.006 | 0.226–0.435 | 3.37 | 30.3 | 42.0 |
LL-37 (pg/mL) | 0.634 | 0.070 | 0.029 | 0.498–0.770 | 323 | 69.7 | 50.7 |
Note: Bold type indicates specificity and/or sensitivity values are greater than 80%.
Abbreviations: ROC, Receiver operating characteristic; CRP, C-reactive protein; NF-κB, nuclear factor-kappaB; AUC, area under the curve.