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. 2019 Jan 25;14:819–834. doi: 10.2147/IJN.S190946

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© 2019 Gajendiran et al. This work is published and licensed by Dove Medical Press Limited

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(A) General scheme of synthesis of 5FU-loaded FA-polymer-AuNP nanoconjugates, graphical representation of (B) 5FU-loaded FA-CPEG-AuNP, (C) 5FU-loaded FA-MAP-AuNP, and (D) 5FU-loaded FA-TAP-AuNP nanoconjugates.

Abbreviations: AuNP, gold nanoparticles; CPEG, citrate polyethylene glycol; EDC, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide; FA, folate; 5FU, 5-fluorouracil; MAP, malate polyethylene glycol; NHS, N-hydroxy succinimide; TAP, tartrate polyethylene glycol.