Table 2.
BMI (body mass index) and insulin dosages
| T0 | T3 | T6 | T9 | T12 | |
|---|---|---|---|---|---|
| BMI (kg/m2) (mean ± SEM) |
25.93 ± 0.51 n = 114 |
26.28 ± 0.58 n = 100 NS |
26.69 ± 0.62 n = 91 P < .05 vs T0 |
26.39 ± 0.59 n = 80 NS |
26.5 ± 0.63 n = 64 NS |
| BMI (kg/m2), HBAlc >7.5% at T0 (mean ± SEM) |
26.45 ± 0.59 n = 91 |
26.92 ± 0.67 n = 80 NS |
27.57 ± 0.72 n = 71 P < .05 vs T0 |
27.35 ± 0.70 n = 59 P < .05 vs T0 |
27.32 ± 0.76 n = 46 NS |
| BMI (kg/m2), HBA1c < 7.5% at T0 (mean ± SEM) |
23.89 ± 0.81 n = 23 |
23.75 ± 0.87 n = 20 NS |
23.57 ± 0.9 n = 20 NS |
23.69 ± 0.85 n = 21 NS |
24.37 ± 0.91 n = 18 NS |
| Long‐acting insulin (U/d) (mean ± SEM) |
28.28 ± 1.653 n = 117 |
25.81 ± 1.489 n = 107 P < .05 vs T0 |
26.49 ± 1.694 n = 96 P < .05 vs T0 |
24.54 ± 1.397 n = 82 P < .05 vs T0 |
24.16 ± 1.456 n = 67 P < .05 vs T0 |
| Long‐acting insulin (U/d), HBAlc > 7.5% at T0 (mean ± SEM) |
29.91 ± 1.99 n = 93 |
27.30 ± 1.800 n = 83 P < .05 vs T0 |
28.38 ± 2.059 n = 74 P < .05 vs T0 T0 |
26.45 ± 1.695 n = 60 P < .05 vs T0 |
25.83 ± 1.713 n = 49 NS |
| Long‐acting insulin (U/d), HBAlc < 7.5% at T0 (mean ± SEM) |
21.98 ± 1.892 n = 24 |
20.68 ± 2.039 n = 24 NS |
20.12 ± 2.144 n = 22 NS |
19.33 ± 2.071 n = 22 P < .05 vs T0 |
19.61 ± 2.536 n = 18 NS |
| Rapid‐acting insulin (U/d) (mean ± SEM) |
28.37 ± 1.556 n = 114 |
29.10 ± 1.924 n = 102 NS |
29.97 ± 1.982 n = 93 P < .05 vs T0 |
30.03 ± 2.023 n = 80 P < .001 vs T0 P < .05 vs T3 |
29.08 ± 2.09 n = 63 NS |
| Rapid‐acting insulin (U/d), HBAlc > 7.5% at T0 (mean ± SEM) |
29.87 ± 1.827 n = 91 |
30.65 ± 2.334 n = 80 NS |
31.65 ± 2.427 n = 72 NS |
32.24 ± 2.56 n = 59 P < .001 vs T0 |
31.03 ± 2.758 n = 44 NS |
| Rapid‐acting insulin (U/d), HBAlc < 7.5% at T0 (mean ± SEM) |
22.43 ± 2.37 n = 23 |
23.45 ± 2.476 n = 22 NS |
24.19 ± 2.48 n = 21 NS |
23.81 ± 2.355 n = 21 NS |
24.58 ± 2.488 n = 19 NS |
| Total insulin/weight (U/kg/d) (mean ± SEM) |
0.71 ± 0.026 n = 114 |
0.69 ± 0.027 n = 92 P < .05 vs T0 |
0.70 ± 0.031 n = 85 NS |
0.69 ± 0.029 n = 73 NS |
0.69 ± 0.035 n = 54 NS |
| Total insulin/weight (U/kg/d), HBAlc > 7.5% at T0 (mean ± SEM) |
0.74 ± 0.031 n = 91 |
0.7 ± 0.034 n = 72 P < .05 vs T0 |
0.72 ± 0.038 n = 67 NS |
0.71 ± 0.036 n = 53 NS |
0.73 ± 0.044 n = 38 NS |
| Total insulin/weight, (U/kg/d), HBAlc < 7.5% at T0 (mean ± SEM) |
0.62 ± 0.034 n = 23 |
0.63 ± 0.034 n = 20 NS |
0.64 ± 0.046 n = 18 NS |
0.62 ± 0.041 n = 20 NS |
0.60 ± 0.051 n = 16 NS |