Table 3.
Clinical, anatomical, cytogenetic, hormonal and histological data of 9 Prader‐Willi syndrome males who underwent testicular biopsy
| Case | Age (y) | Genetic defect | Biopsy side | Cryptorchidism | Site of testis | Length (mm) | Nistal score | hCG stimulation test | Post Puberty | Pubertal stage | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T (ng/dL) | Age (y) | LH (mIU/mL) | FSH (mIU/mL) | T (ng/dL) | |||||||||
| Peak | |||||||||||||
| 1 | 1.3 | DEL | Lt | Lt | Intra‐abdominal | 16 | I | 300.4 | 13 | 8.2 | 20.4 | 391.8 | 3 |
| 2 | 1.4 | Not known | Rt | Rt | Extra‐canalicular | 10 | I | 59.4 | 15 | 0.2 | 1.0 | 27.8 | 2 |
| 3 | 1.4 | DEL | Rt | Bil | Extra‐canalicular | Unknown | III | Unknown | 21 | 4.9 | 29.6 | 508.7 | 3 |
| 4 | 2.6 | DEL | Rt | Rt | Extra‐canalicular | Unknown | III(SCOS) | Unknown | 21 | 4.9 | 30.3 | 202.6 | 5 |
| 5 | 6.3 | DEL | Rt | Bil | Extra‐canalicular | 12 | III(SCOS) | Unknown | 18 | 5.3 | 18.8 | 162.5 | 2 |
| 6 | 1.6 | UPD | Lt | Bil | Extra‐canalicular | 9 | II | 867.9 | Puberty not reached | ||||
| 7 | 1.2 | UPD | Lt | Bil | Intra‐canalicular | 9 | III | 249.3 | Puberty not reached | ||||
| 8 | 1.6 | DEL | Rt | Bil | Extra‐canalicular | 10 | III | Unknown | Puberty not reached | ||||
| 9 | 2.5 | DEL | Rt | Bil | Extra‐canalicular | 11 | III(SCOS) | Unknown | Puberty not reached | ||||
Bil, bilateral; DEL, deletion; Lt, left; Rt, right; SCOS, Sertoli Cell‐Only Syndrome; T, testosterone; UPD, uniparental disomy.