Figure 3.
Scatter plots of combinations of parameter estimates from the simulation of type 3 tumor curves and a signal to noise ratio (SNR) of 20 (top row) and 50 (bottom row). The middle panel (ve vs PS plot) demonstrates that the optimization process generates imprecise ve estimates, particularly for method 3 (grey circles). However, as the SNR increases the precision increases. Note that Fb, PS and vb are estimated with a higher accuracy and precision than ve. The white cross indicates the ground truth of the parameters.