Table 1.
Summary of Results.*
| Age | Gen | Allele | Exp ** | LOE | Obstetric History | Children with FM | Children with PM | Menopau se (Age) | FXPOI | FXTAS | Seizures | Cognit | Anxiety | Comments |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 71 | F | 30,57 | Y | 40 | G0P0 | 0 | 0 | 39 | * | |||||
| 38 | F | 30,55 | N | G3P3L3 | 0 | 1 (M) | NO | |||||||
| 44 | F | 30, 142 | Y | 15 | G2P2 | 2 (M) | 0 | 38 | * | * | Mild anxiety | |||
| 54 | F | 30,55 | N | G4P5L4 | 0 | 1 (F) | 51 | |||||||
| 53 | F | 30,69 | Y | 10 | G0P0 | 0 | 0 | 51 | * | Mutism | ||||
| 60 | F | 30,110 | Y | 30 | G0P0 | 0 | 0 | 55 | * | Cerebral atrophy | ||||
| 54 | F | 45,135 | Y | 20 | G1C1 | 1 (M) | 50 | * | * | Cerebellar atrophy, ataxia started at 42 yo | ||||
| 80 | F | 29,86 | Y | 35 | G9P9 | 3 (M) 1 (F) |
1 (F) | 51 | * | Tremor started at 75 yo | ||||
| 68 | F | 29,105 | Y | 15 | G4P4 | 1 (M) | 1 (F) | 57 | ||||||
| 53 | F | 30,82 | Y | 25 | G5P3C2 L2 | 0 | 0 | 35 | * | * | * | Cerebral atrophy, hysterectomy 35 yo, moderate anxiety, tremor started at 46 yo | ||
| 26 | F | 39,77 | N | G2C1L0 | 0 | 0 | NO | |||||||
| 71 | F | 30,67 | Y | 40 | G0P0 | 0 | 0 | 50 | * | * | * | Intellectual disability, severe anxiety | ||
| 49 | F | 30,79 | N | G2P2 | 1 (M) | 1 (F) | 47 | |||||||
| 47 | F | 30,82 | N | G1P1 | 0 | 0 | NO | |||||||
| 57 | F | 30,80 | N | G2P2 | 2 (M) | 0 | 48 | |||||||
| 47 | F | 30,71 | N | G3P3L2 | 0 | 0 | 45 | * | Moderate anxiety | |||||
| 39 | F | 30,66 | Y | 21 | G3P2C1 | 0 | 1 (M) | 36 | * | * | ||||
| 65 | F | 29,82 | N | G1P1 | 0 | 1 (F) | 50 | |||||||
| 62 | F | 30,121 | Y | 35 | G4P2C2 L3 | 2 (F) | 0 | 51 | ||||||
| 38 | F | 29,102 | N | G1P1 | 0 | 0 | NO | |||||||
| 11 m | M | 55 | N | 0 | 0 | 0 | NA | |||||||
| 16 | M | 55 | N | 0 | 0 | 0 | NA | * | Mild anxiety | |||||
| 83 | M | 69 | Y | 40 | 3 (F) 4 (M) | 0 | 3 (F) | NA | * | Tremor started at 75yo | ||||
| 70 | M | 61 | Y | 40 | 4 (F) 3 (M) | 0 | 3 (F) | NA | * | * | Disinhibition and emotion regulation problems, moderate anxiety | |||
| 14 | M | 123 | N | 0 | 0 | 0 | NA |
All patients are Hispanic. Gen=Gender; Exp=Exposed to pesticides; Y=yes; N=no; LOE=Length of pesticide exposure (in years); Cognit=Cognitive; PM=premutation; FM=full mutation; NA=not applicable; M=male and F=female; G=gravida (number of pregnancies), P=para (number of pregnancies reaching viable gestational age) C=cesarean delivery and L= living children.
Those exposed have worked in the field, some of them since childhood. The length of exposure to each specific pesticide is unknown since their use depends on the type of crop. Products commonly grown include cotton, milo, tomato, papaya, pineapple and sugar cane. Younger generations have had better educational resources and have transitioned to more diverse job opportunities in nearby cities. However; agriculture remains to be the main economic activity of the region. No one is exempt from exposure one way or another.