Table 1. Metabolic and cardiovascular risk parameters according to the different clinical categories of dysglycemia during the first phase of the study (1998–1999).
| Total population | Normoglycemia | Prediabetes | Unknown diabetes | Diagnosed diabetes | P-value | |
|---|---|---|---|---|---|---|
| Patients (n) | 1034 | 607 | 296 | 83 | 48 | <0.001 |
| Men (%) | 473 (45.7) | 238 (39.2) | 160 (54.1) | 47 (57.6) | 28 (58.3) | <0.001 |
| Age (years) | 52.1±13.4 | 49.4±3 | 56.5±12 | 61.5±11.2 | 65.6±8.6 | <0.001 |
| Smokers (%) | 293 (28.3) | 177 (29.2) | 65 (22) | 19 (22.9) | 10 (20.8) | <0.001 |
| Previous CVD (%) | 49 (4.7) | 12 (2) | 19 (6.4) | 9 (10.8) | 9 (18.8) | 0.001 |
| Estimated body fat (%) | 34.6±8.1 | 33.6±7.7 | 35.6±8.4 | 37.7±7.7 | 36.0±9.7 | <0.001 |
| BMI (kg/m2) | 27.6±4.7 | 26.5±4.3 | 28.9±4.4 | 30.5±4.8 | 28.9±5.7 | <0.001 |
| SBP (mmHg) | 134.2±22.1 | 127.4±19.4 | 139.9±21 | 151.6±21.1 | 155.3±22.8 | <0.001 |
| DBP (mmHg) | 83.7±13.5 | 80.1±12.4 | 87.5±13.7 | 91±13.2 | 91.8±11.6 | <0.001 |
| Total cholesterol (mg/dL) | 223.45.5 | 223.9±40.6 | 236.4±43.4 | 240.7±38.4 | 235.9±95.4 | <0.001 |
| HDL cholesterol (mg/dL) | 56.3±14.2 | 58.3±14.7 | 54.2±12.6 | 51.8±14.2 | 51.7±12.9 | <0.001 |
| LDL cholesterol (mg/dL) | 149.6±37.0 | 145.7±36.6 | 156.3±38.4 | 158.6±33.5 | 141.3±30.9 | <0.001 |
| TG (mg/dL) | 125.0±61.3 | 102.8±66.1 | 130.5±65.7 | 154.3±78.3 | 152.5±77.8 | <0.001 |
| eGFR (ml/min) | 78.6±19.3 | 83.1±18.9 | 73.6±18.1 | 71.5±17 | 65.6±19.1 | <0.001 |
| Fasting glucose (mg/dL) | 100.2±23.5 | 89.6±6.2 | 104.6±9.0 | 123.4±23.3 | 168±56.2 | <0.001 |
| HbA1c (%) | 5.3±0.8 | 5±0.4 | 5.3±0.4 | 6±1 | 7.5±1.7 | <0.001 |
Abbreviations: CVD, cardiovascular disease; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglycerides; eGFR, estimated glomerular filtration rate; HbA1c, glycohemoglobin.