Table 4. Unadjusted and adjusted odds ratios for anti-DENV IgG and anti-CHIKV IgG seropositivity among blood donors residing in Qatar but from different regions.
Characteristic | Unadjusted Odds Ratio | Adjusted Odds Ratioa | ||||||
---|---|---|---|---|---|---|---|---|
Anti-DENV IgG UOR (95% CI) |
P value | Anti-CHIKV IgG UOR (95% CI) |
P value | Anti-DENV IgG AOR (95% CI) |
P value | Anti-CHIKV IgG AOR (95% CI) |
P value | |
Region | ||||||||
Asia | Ref | Ref | Ref | Ref | ||||
Middle East | 0.05 (0.03–0.06) | <0.001 | 0.09 (0.05–0.16) | <0.001 | 0.05 (0.04–0.07) | <0.001 | 0.14 (0.07–0.27) | <0.001 |
North Africa | 0.14 (0.10–0.20) | <0.001 | 0.37 (0.20–0.67) | 0.001 | 0.14 (0.10–0.20) | <0.001 | 0.50 (0.26–0.96) | 0.038 |
Qatar | 0.01 (0.01–0.03) | <0.001 | 0.23 (0.10–0.53) | <0.001 | 0.01 (0.01–0.03) | <0.001 | 0.38 (0.15–0.96) | 0.041 |
Age group (years) | ||||||||
≤ 24 | Ref | Ref | Ref | Ref | ||||
25–29 | 2.51 (1.44–4.36) | 0.001 | 1.95 (0.64–5.97) | 0.243 | 1.20 (1.05–3.79) | 0.035 | 1.23 (0.39–3.89) | 0.721 |
30–34 | 2.98 (1.74–5.08) | <0.001 | 1.95 (0.66–5.80) | 0.229 | 2.38 (1.28–4.41) | 0.006 | 1.21 (0.40–3.70) | 0.740 |
35–39 | 2.58 (1.50–4.43) | 0.001 | 1.02 (0.31–3.29) | 0.978 | 2.42 (1.30–4.51) | 0.006 | 0.69 (0.21–2.29) | 0.541 |
40–44 | 2.30 (1.32–4.01) | 0.003 | 1.84 (0.60–5.70) | 0.288 | 2.40 (1.25–4.56) | 0.008 | 1.42 (0.45–4.52) | 0.551 |
45–49 | 2.87 (1.60–5.16) | <0.001 | 2.62 (0.83–8.28) | 0.102 | 2.26 (1.13–4.50) | 0.021 | 1.65 (0.51–5.42) | 0.406 |
≥ 50 | 2.48 (1.37–4.50) | 0.003 | 1.51 (0.43–5.25) | 0.517 | 3.18 (1.61–6.28) | 0.001 | 1.28 (0.36–4.59) | 0.704 |
Anti-DENV IgG positive | — | — | 4.68 (2.98–7.34) | <0.001 | — | — | 1.94 (1.09–3.44) | 0.024 |
Anti-CHIKV IgG positive | 4.68 (2.98–7.34) | <0.001 | — | — | 1.94 (1.09–3.44) | 0.024 | — | — |
a Adjusted for nationality, age, and other arbovirus seropositivity (i.e. anti-DENV seropositivity status as predictor of anti-CHIKV seropositivity, and vice versa). For this analysis, n = 1,989 given missing age information for three individuals.