| Aktug-Demir et al., 2014 |
Turkey (75) |
Arthralgia |
Blood culture |
Standard tube agglutination test |
Contrast enhanced MRI |
| Al-Eissa et al., 1990 |
Saudi Arabia (40) |
N/A |
Blood culture |
Brucella microagglutination test |
N/A |
| Ariza et al., 1993 |
Spain (62) |
N/A |
N/A |
Standard tube agglutination test, Rose Bengal test, Coombs test |
Plain radiographs, bone radionuclide scan |
| Aydoslu et al., 2006 |
Turkey (14) |
N/A |
Blood culture |
N/A |
N/A |
| Benjamin et al., 1992 |
Saudi Arabia (57) |
N/A |
Blood culture |
N/A |
N/A |
| Benjamin and Khan, 1994 |
Saudi Arabia (70) |
Pain, swelling, redness, functional disability |
Blood and synovial fluid culture |
Standard tube agglutination test |
Plain radiographs |
| Besharat et al., 2010 |
Iran (56) |
Pain, fever, sweating |
N/A |
N/A |
N/A |
| Bosilkovski et al., 2004a |
Macedonia (196) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test, Brucella Coombs test |
Fabere test, plain radiograph, MRI, computed tomography, radionuclide bone scan, ultrasound |
| Bosilkovski et al., 2004b |
Macedonia (162) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test, Brucella Coombs test |
Plain radiographs, bone radionuclide scan, ultrasound, MRI |
| Bosilkovski et al., 2010 |
Macedonia (299) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test, Brucella Coombs test, Brucellacapt test |
MRI, radionuclide bone scans, computerized tomography |
| Bosilkovski et al., 2013 |
Macedonia (133) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test, Brucella Coombs test, Brucellacapt test |
Stinchfield, Mennel test, abnormality on radiography, radionuclide bone scan or ultrasound examination, MRI, computed tomography |
| Bukharie, 2009 |
Saudi Arabia (54) |
Fever, pain |
Blood and bone marrow culture |
Standard tube agglutination test, ELISA (IgM and IgG) |
N/A |
| Bulut et al., 2011 |
Turkey (84) |
Fever, sweating, arthralgia |
Blood culture |
Standard tube agglutination test |
Plain radiographs, computed tomography scan, bone scan, MRI |
| Cirakli et al., 2015 |
Turkey (11) |
N/A |
Body fluid culture |
Standard tube agglutination test |
N/A |
| Colmenero et al., 1991 |
Spain (65) |
Pain, swelling, redness, functional disability |
N/A |
Seroagglutination, Coombs, indirect immunofluorescence, Rose Bengal |
Plain radiographs, radionuclide bone scan |
| Colmenero et al., 1992 |
Spain (58) |
Pain, swelling, redness, functional disability |
N/A |
Wright, Coombs, rose bengal test, indirect immunofluorescence |
Plain radiographs, bone radionuclide scan |
| Colmenero et al., 1996 |
Spain (2) |
N/A |
N/A |
Wright, Coombs, indirect immunofluorescence |
Computed tomography |
| Colmenero et al., 2008 |
Spain (96) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test, Coombs antibrucella or immunocapture agglutination test |
Computed tomography |
| Dabbagh and Rasool 2009 |
Iraq (45) |
Pain, swelling, and restriction of movement |
N/A |
Brucella agglutination test and 2-Mercaptoethanol |
Plain radiograph |
| Dahouk et al., 2005 |
Germany (11) |
N/A |
Blood culture |
Standard tube agglutination test, ELISA IgM, IgG |
N/A |
| Demiroglu et al., 2007 |
Turkey (51) |
N/A |
Bone marrow, sternoclavicular and psoas abscess culture |
Standard tube agglutination test |
N/A |
| Ebrahimpour et al., 2017 |
Iran (464) |
Swelling, effusion, restriction of movement |
N/A |
Standard tube agglutination test and 2-Mercaptoethanol |
Plain radiographs, MRI, sonography |
| Eini et al., 2012 |
Iran (118) |
Arthralgia |
Blood culture |
Standard tube agglutination test, Brucella Coombs test, 2-Mercaptoethanol |
N/A |
| Fanni et al., 2013 |
Iran (26) |
N/A |
Blood and bone marrow culture |
Serum agglutination test, Wright and Coombs test, 2-Mercaptoethanol |
N/A |
| Fruchtman et al., 2015 |
Israel (92) |
Fever, myalgia, headache |
Blood culture |
Standard tube agglutination test |
N/A |
| Gonen et al., 2013 |
Turkey (50) |
|
Blood and synovial fluid and bone marrow culture |
Standard tube agglutination test, Coombs test |
Plain radiographs, MRI, computed tomography, ultrasonography |
| Gotuzzo et al., 1987 |
Peru (22) |
N/A |
Blood, bone marrow, synovial culture |
N/A |
N/A |
| Guler et al., 2014 |
Turkey (178) |
Pain, swelling, redness, functional disability |
Blood culture |
Standard tube agglutination test |
Radiological alterations and/or radionuclide uptake in any deep joint |
| Gur et al., 2003 |
Turkey (195) |
Pain, swelling, redness, functional disability |
Blood and body fluid culture |
Standard tube agglutination test |
Plain radiographs, bone radionuclide scan, computed tomography, MRI |
| Hizel et al., 2007 |
Turkey (72) |
Pain, fever |
Blood culture |
Standard tube agglutination test |
Bone Scintigrapghy |
| Issa and Jamal, 1999 |
Jordan (38) |
Arthralgia |
Blood and bone marrow culture |
Rose Bengal test, ELISA IgM and IgG, Wright test |
N/A |
| Jia et al., 2017 |
China (137) |
Fatigue, fever, muscle and joint pain, headache |
Blood culture |
Standard tube agglutination test |
N/A |
| Kazak et al., 2016 |
Turkey (87) |
Arthralgia |
Blood and body fluid culture |
Standard tube agglutination test and Rose bengal test, |
N/A |
| Khateeb et al., 1990 |
Kuwait (104) |
Pain, swelling, restriction of movement |
Culture negative |
Microagglutination, slide agglutination test, ELISA (IgG, IgM, and IgA) |
Plain radiographs- no apparent pathological changes |
| Kokoglu et al., 2006 |
Turkey (64) |
N/A |
Blood and body fluids culture |
Wright agglutination test |
N/A |
| Kose et al., 2014 |
Turkey (10) |
Arthralgia |
Blood and bone marrow culture |
Standard tube agglutination test |
N/A |
| Kouba et al., 2013 |
Tunisia (32) |
Pain |
Blood and body fluids/tissue culture |
Standard tube agglutination test |
MRI, computed tomography |
| Kursun et al, 2013 |
Turkey (137) |
Arthralgia |
Blood and bone marrow culture |
Standard tube agglutination test |
Whole-body bone scintigraphy (Technetium 99m) |
| Lulu et al., 1988 |
Kuwait (105) |
Pain and swelling |
Culture negative |
Microagglutination, slide agglutination test, ELISA (IgG, IgM, and IgA) |
N/A |
| Memish et al., 2000 |
Saudi Arabia (68) |
N/A |
Blood and body fluid culture |
Microagglutination test |
N/A |
| Memut et al., 2012 |
Turkey (70) |
Pain, swelling, redness, functional disability |
Blood and bone marrow culture |
Standard tube agglutination test, Rose Bengal test |
Computed tomography, MRI |
| Mugahi et al., 2014 |
Iran (8) |
Arthralgia |
N/A |
Wright test and 2-Mecarptoethanol test |
N/A |
| Namiduru et al., 2003 |
Turkey (14) |
Arthralgia |
Blood and body fluid culture |
Wright test |
Plain radiograph, bone scintigraphy, MRI |
| Okur et al., 2012 |
Turkey (20) |
Arthralgia |
Blood culture |
Standard tube agglutination test |
N/A |
| Parlak et al., 2015 |
Turkey (55) |
N/A |
Blood culture |
Brucella agglutination test, standard tube agglutination test |
None |
| Pourbagher et al., 2006 |
Turkey (114) |
Arthralgia |
Blood culture |
Standard tube agglutination test |
Joint sonography, radiography, radionuclide, bone scintigraphy, and MRI |
| Qehaja-Bucaj et al., 2015 |
Kosovo (55) |
Fever, arhtralgia, fatigue, sweating |
N/A |
Wright test |
Plain radiographs |
| Roushan et al., 2004 |
Iran (69) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test, 2-Mercaptoethanol |
Plain radiographs, bone radionuclide scan |
| Roushan et al., 2005 |
Iran (35) |
Pain, swelling, redness, functional disability |
Blood culture |
Standard tube agglutination test, 2-Mercaptoethanol |
Radionuclide scan |
| Santiago et al., 2011 |
Portugal (44) |
N/A |
|
|
N/A |
| Sasan et al., 2012 |
Iran (52) |
Arthralgia |
Blood, urine and joint fluid culture |
Wright test, Coombs test, Rose Bengal test, and 2-Mercaptoethanol |
N/A |
| Savas et al., 2007 |
Turkey (74) |
Arthralgia |
Blood culture |
Standard tube agglutination test |
N/A |
| Tasova et al., 1999 |
Turkey (87) |
Pain, swelling, redness, functional disability |
Blood and body fluid culture |
Standard tube agglutination test |
Plain radiograph, radionuclide bone scan |
| Ulug et al., 2011 |
Turkey (5) |
Pain, swelling, redness, functional disability |
N/A |
Standard tube agglutination test |
Computed tomography, MRI, plain Radiograph |
| Zaks et al., 1995 |
Israel (40) |
Pain, swelling, redness, functional disability |
Positive culture |
Standard tube agglutination test, Rose Bengal test, 2-Mercaptoethanol |
Plain radiographs |
| Zamani et al., 2011 |
Iran (24) |
Pain, swelling, redness, functional disability |
Blood culture |
Standard tube agglutination test, 2-Mercaptoethanol |
N/A |
