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. 2018 Jun 22;33(1):181–194. doi: 10.1096/fj.201800459R

Figure 2.

Figure 2

Muscle Igf1 deletion induces loss of muscle mass. A) Normalized masses of hind limb muscles were not different between bMID and control mice at all time points examined (4, 8, 12, and 16 wk) across all muscle groups (n = 8–15). B) Total number of fibers decreased in bMID EDL muscles (n = 3–7) at 4 wk of age. C) There was an increase in median Feret diameter at 4 wk between bMID and control EDL fibers. Values are means ± sem. Statistical analysis was performed with a 2‐tailed Student’s t test with effect size presented as Cohen’s d. *P < 0.05, **P < 0.01 (bMID vs. control), ††P < 0.01 (comparisons within strain).