TABLE 3.
GO analysis of genes significantly up-regulated
| GO ID | Description | P | FDR q |
|---|---|---|---|
| 0044710 | Single-organism metabolic process | 2.77E−05 | 1.52E−01 |
| 0006091 | Generation of precursor metabolites and energy | 7.32E−05 | 2.00E−01 |
| 0008152 | Metabolic process | 2.86E−04 | 5.22E−01 |
| 0006518 | Peptide metabolic process | 6.46E−04 | 8.85E−01 |
| 0055114 | Oxidation–reduction process | 9.36E−04 | 1.00E+00 |
The ontology analysis shows genes significantly up-regulated ≥2-fold in SRC-2–CKO + AICAR mice vs. WT + saline controls from RNA sequencing on total heart RNA before TAC surgery. FDR, false-discovery rate.