Figure 6.

Analysis of phototransduction protein localization in Mks6^Δ retinas. A) Transducin staining (green) is similar between Mks6^Δ mutants and Mks6^FL controls in both the light and dark conditions. B) Rhodopsin staining (green) in both light- and dark-adapted conditions reveals slight mislocalization in the IS (arrows) in juvenile Mks6^Δ mutants compared with Mks6^FL controls. C) Arrestin staining (green) is present in the OS and is mislocalized to the IS and ONL in the light-adapted Mks6^Δ mutant retinas (asterisk). One-way ANOVA was used for quantification of the average fluorescence intensity distribution indicated for each protein in the graphs (right). DAPI-stained nuclei are blue. Original scale bar, 25 µm.