Fig. 6.

GLANET regulatory sequence analysis for the OCD SNPs annotated with TFs in the library. (a) SNP rs1891215 located at chr1:7,667,794 changes reference nucleotide A to G, and as a result, leads to a better match to the STAT1 PFM, i.e. the P-value of the match to the STAT1 PFM changes from 1.1e-3 to 6.1e-5. (b) SNP rs10946279 (chr6:170,553,248) changes reference nucleotide C to T, thereby decreasing the significance of the match to the MAX PFM, i.e. the P-value of the match increases from 6.1e-5 to 1.5e-3