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The expression of CXCR4 and CXCL12 mRNA in human preovulatory follicles. Human ovarian follicles were collected at three preovulatory phases: pre-, early, and late ovulatory phases (mean ± SEM; n = 5–6 women/phase). The levels of CXCR4 (A) and CXCL12 (B) mRNA in granulosa cells were measured using real-time PCR and normalized to the GAPDH in each sample. Bars with no common superscripts are significantly different (P < 0.05).
