Table 1. Baseline characteristics and laboratory results of included patients.

	ACLF (n = 40)	decompensated (n = 51)	compensated (n = 26)	P-value (ACLF vs. decompensated)	P-value (decompensated vs. compensated)
Age (years), mean (SD)	55 (10)	55 (11)	55 (12)	0.7	1.0
Male gender, n (%)	30 (75.0)	36 (70.5)	17 (65.4)	0.8	0.8
BMI (kg/m2), mean (SD)	27.8 (6.8)	25.2 (5.7)	26.4 (5.9)	0.2	0.6
Origin of cirrhosis
Alcohol, n (%)	23 (58)	30 (59)	13 (50)	1.0	0.8
HCV/HBV, n (%)	4 (10)	4 (8)	5 (19)	1.0	0.4
NASH, n (%)	2 (5)	3 (9)	1 (4)	1.0	1.0
Other, n (%)	11 (28)	14 (27)	7 (27)	1.0	1.0
Laboratory data
Leucocytes (/nl), mean (SD)	11.97 (6.67)	8.47 (4.88)	6.1 (5.1)	0.01	0.003
Hemoglobin (g/dl), mean (SD)	9.3 (1.7)	10.7 (2.8)	11.1 (2.3)	0.008	0.6
Platelets (/nl), mean (SD)	108 (72)	135 (97)	107 (61)	0.1	0.3
CRP (mg/dl), mean (SD)	5.4 (4.6)	2.7 (2.9)	1.5 (2.1)	<0.001	0.07
Sodium (mmol/l), mean (SD)	129 (20)	135 (6)	136 (4)	0.06	0.4
Creatinine (mg/dl), mean (SD)	2.7 (1.4)	1.0 (0.4)	0.90 (0.30)	<0.001	0.2
Bilirubin (mg/dl), mean (SD)	15.1 (13.7)	7.1 (9.3)	4.6 (5.7)	0.01	0.2
ALT (U/l), mean (SD)	51 (40)	53 (45)	36 (26)	0.8	0.09
γGT (U/l), mean (SD)	191 (187)	164 (183)	146 (144)	0.3	1.0
INR, mean (SD)	2.16 (0.86)	1.53 (0.45)	1.45 (0.35)	<0.001	0.6
Albumin (g/dl), mean (SD)	2.9 (0.6)	2.8 (0.5)	3.2 (0.7)	0.9	0.1
Docosahexaenoic acid (ng/ml), mean (SD)	17 (11)	18 (14)	18 (19)	0.8	0.6
Arachidonic acid (ng/ml), mean (SD)	2060 (1035)	2524 (2735)	1972 (929)	0.8	0.9
ARA/DHA, mean (SD)	147 (77)	161 (70)	166 (78)	0.2	0.6

ALT, alanine aminotransferase; ARA, arachidonic acid; AST, aspartate aminotransferase; BMI, body mass index; CRP, C-reactive protein; DHA, docosahexaenoic acid; γGT, γ-glutamyl transferase; HBV, hepatitis B virus; HCV, hepatitis C virus; INR, international normalized ratio; NASH, nonalcoholic steatohepatitis; SD, standard deviation