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. Author manuscript; available in PMC: 2020 Jan 30.
Published in final edited form as: ACS Appl Mater Interfaces. 2019 Jan 17;11(4):3629–3644. doi: 10.1021/acsami.8b14744

Table 4.

Comparison of (Photo)toxicities of Complexes 3 and 5 Toward SK-MEL-28 Cancer Cells.

Complex Dark Vis lighta Red lightc

EC50 / μM EC50 / μM PIb EC50 / μM PId

3 67.0±0.91 0.27±0.01 248 58.9±0.69 1
5 > 300 0.69±0.01 > 435 136±5.73 > 2
a

16 hours drug-to-light interval followed by 100 J·cm−2 broadband visible light irradiation,

b

PI = phototherapeutic index (ratio of dark EC50 to visible-light EC50),

c

16 hours drug-to-light interval followed by 100 J·cm−2 light irradiation with 625-nm LEDs,

d

PI = phototherapeutic index (ratio of dark EC50 to red-light EC50).