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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Jul 31;11(2):e1541. doi: 10.1002/wnan.1541

FIGURE 5.

FIGURE 5

Nanoscale metal organic layers for X-PDT. (a) Schematic for Hf-based nMOL X-PDT agent. (b) Photosensitizers. Top: Ir[2,2′-bipyridine (2-phenylpyridine)2]+. Bottom: [Ru(2,2′-bipyridine)3]2+ c) physical characterization. Top left: TEM nMOL bottom left: HRTEM image, inset: FFT pattern. Top right: Tapping-mode AFM topography. Bottom right: Height profile along the white line. d) SOSG assay results. Samples were treated by 225 kVp irradiation. (e) in vivo therapeutic effect of nMOL (left:CT26, right:MC38). (Reprinted with permission from Lan et al. (2017). Copyright 2017 John Wiley and Sons)