Table 4:

Regions defined by their MNI coordinates that showed significant GM differences in the UCLA sample between IBS patients and HC.

				MNI Coordinates
Region	Voxels	t	p(FDR)	X	Y	Z
CLUSTER (IBS < HC)	953	3.45	0.001	−6	16	−14
L Caudate Nucleus		5.01	0.002	−10	14	0
L Nacc		5.15	0.002	−10	−16	−8
R Thalamus		4.56	0.002	10	−12	18
L Thalamus	4	3.82	0.002	−16	−28	14

Sample show female adolescents with IBS exhibit lower GMV in the bilateral thalamus and left caudate nucleus and left nucleus accumbens.

Abbreviations: Nacc: nucleus accumbens. L: left, R: right, t : t-value, p(FDR): corrected p-value using the false discovery rate.