Figure 2.

Functional annotation of NEAT1 signature in multiple myeloma (MM). (A) Enrichment plots of four selected gene sets detected by gene set enrichment analysis. The green curves show the enrichment score and reflect the degree to which each gene (black vertical lines) is represented at the bottom of the ranked gene list. Genes contributing to the core enrichment (CE) in the gene set are indicated in bold with Y. (B) Heatmap of the 138 differentially expressed genes identified by comparing the first versus fourth quartile of 50 MM patients stratified into four groups based on NEAT1 expression level.