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. 2018 Sep 27;104(2):360–369. doi: 10.3324/haematol.2018.195032

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Figure 2. — Subgroups of patients with similar prognosis within mutated chronic lymphocytic leukemia (M-CLL) and unmutated chronic lymphocytic leukemia (U-CLL). (A) TP53abn, trisomy 12 (+12) and stereotyped subset #2 assignment define three almost non-overlapping groups within early stage M-CLL. (B) Binet A M-CLL cases with TP53abn, +12 or assignment to stereotyped subset #2 display similar time-to-first-treatment (TTFT.) (C) Distribution of TP53abn, SF3B1 mutations and del(11q) in Binet A U-CLL. (D) Binet A U-CLL cases carrying TP53abn, SF3B1 mutations or del(11q) exhibit similar TTFT. N: number of patients.