Fig. 1.

Bioenergetics and glycolytic function alterations in porphyria cutanea tarda (PCT) and acute hepatic porphyria (AHP) monocytes as measured using the mitochondrial stress test. Representative bioenergetics (OCR) profiles of CD14+ monocytes of PCT (A) and that of AHP (B) as determined by injecting oligomycin, FCCP and antimycin A sequentially. Measurements are given as mean ± SEM from 3 to 6 assay replicates. Healthy controls shown in black, active porphyria in gray, and porphyria remission in open white circles.