TABLE 4.
Results of NS1 IgM ELISAs in different serum/plasma panels
NS1 IgM ELISAa | No. of IgM+/total samples (%) in different serum/plasma panelsb |
|||||
---|---|---|---|---|---|---|
Naive | pDENV1 | pDENV2 | pZIKV | sDENV | ZIKVwprDENV | |
ZIKV | 0/8 (0) | 0/5 (0) | 18/20 (90) | 1/24 (4) | 11/20 (55) | |
DENV1 | 0/16 (0) | 5/9 (55.6)c | 0/20 (0) | 4/24 (16.7) | 3/20 (15) | |
DENV2 | 0/4 (0) | 5/9 (55.6) | ||||
DENV1-4 | 0/4 (0) | 4/9 (44.4)c | 5/9 (55.6) |
ELISA, enzyme-linked immunosorbent assay; pDENV1, primary DENV1 infection; pDENV2, primary DENV2 infection; pZIKV, primary ZIKV infection; sDENV, secondary DENV infection; ZIKVwprDENV, ZIKV infection with previous DENV infection.
Only samples collected <3 months post-symptom onset were tested for IgM.
IgM+ rate was 3/3 (100%) for samples collected <1 month.