FIG 3.

In vivo efficacies of NFAP2, fluconazole (FLC), and their combination in the murine vulvovaginitis model. The bars represent the means ± SEM (standard errors of the means) of the vaginal tissue burdens of BALB/c mice intravaginally infected with the FLC-resistant C. albicans 27700 isolate. Significant differences (P values) between numbers of CFU were determined based on comparison with the untreated controls. Other significance values existing between the different treatments are presented in Table S2 in the supplemental material. Levels of significant differences are indicated (*, P ≤ 0.05; **, P ≤ 0.005).