FIG 2.

(A) Predicted probability of parasitemia with increasing piperaquine concentration in the absence of indoor residual spraying of insecticide for women receiving DHA-PQ stratified by trimester. The solid lines show the median probabilities and shading encompasses probabilities for 95% of the population. The median probability of parasitemia while receiving SP as IPTp was 39%. Contributions of mutant and wild-type genotypes to overall parasitemia probability during the second trimester for pfmdr1 86 (B) and pfcrt 76 (C). The black lines represent the median probabilities of all parasitemia, and shaded areas indicate the proportions of the probabilities attributed to wild-type and mutant parasites. Results for the third trimester are shown in Fig. S3 in the supplemental material.