TABLE 1.
MICs of preexposure cefiderocol and comparators against a collection of 12 P. aeruginosa, A. baumannii, and Enterobacteriaceae isolates
| Isolate | MIC (μg/ml) fora: |
||||
|---|---|---|---|---|---|
| Cefiderocol | FEP | MEM | CAZ | TZP | |
| AB 135 | 0.5 | ND | 128 | ND | ND |
| AB 152 | 1 | 64 | 128 | ND | ND |
| EC 462 | 1 | >64 | 0.06 | >128 | >128 |
| EC 458 | 1 | 512 | 0.06 | >128 | >64 |
| PSA 1574 | 2 | 8 | 16 | ND | ND |
| PSA 1595 | 4 | 2 | 1 | ND | ND |
| KP 531 | 4 | >64 | 256 | >64 | >32 |
| KP 519 | 4 | >64 | 512 | >32 | >32 |
| KP 539 | 4 | >512 | 0.12 | 128 | 128 |
| AB 87 | 4 | >16 | 256 | >16 | >64 |
| KP 543 | 8 | >512 | ND | ND | ND |
| AB 84 | 16 | >64 | 64 | >16 | >64 |
a
MEM, meropenem; FEP, cefepime; CAZ, ceftazidime; TZP, piperacillin-tazobactam; ND, no data.