TABLE 2.

Whole-genome sequencing for selected isolates from infected animals after 72 h of no treatment or cefiderocol exposure

Isolate	Sample	Regimen at 72 h	MLST	β-Lactamase	Lesion relative to control
E. coli 462	32a	Control	410	blaEC; blaCMY-42	Not applicable
E. coli 462	40a	Cefiderocol	410	blaEC; blaCMY-42	None identified
E. coli 462	41a	Cefiderocol	410	blaEC; blaCMY-42	ΔpcnB, S100A in EMU65688.1
E. coli 462	42b	Cefiderocol	410	blaEC; blaCMY-42	None identified
K. pneumoniae 531	73a	Control	258	blaSHV-12; blaKPC-2	Not applicable
K. pneumoniae 531	82a	Cefiderocol	258	blaSHV-12; blaKPC-2	None identified