Table 1.
PBRM1, BAP1 and H3K36me3 Expression in RCC Subtypes
| Clear Cell n (%) |
Papillary Type 1 n (%) |
Papillary Type 2 n (%) |
Chromophobe n (%) |
Oncocytoma n (%) |
Clear Cell Papillary n (%) |
|
|---|---|---|---|---|---|---|
| PBRM1 | ||||||
| Negative | 306 (68) | 27 (43.5) | 22 (41.5) | 32 (66.7) | 1 (8.3) | 1 (20) |
| Weak | 96 (21.3) | 19 (30.6) | 17 (32.1) | 10 (20.8) | 2 (16.7) | 3 (60) |
| Strong | 48 (10.7) | 16 (25.8) | 14 (26.4) | 6 (12.5) | 9 (75) | 1 (20) |
| Total | 450 | 62 | 53 | 48 | 12 | 5 |
| BAP1 | ||||||
| Negative | 193 (40.4) | 5 (7.5) | 9 (15.8) | 21 (45.7) | 0 (0) | 1 (20) |
| Weak | 205 (42.9) | 32 (47.8) | 31 (54.4) | 21 (45.7) | 5 (38.5) | 2 (40) |
| Strong | 80 (16.7) | 30 (44.8) | 17 (29.8) | 4 (8.6) | 8 (61.5) | 2 (40) |
| Total | 478 | 67 | 57 | 46 | 13 | 5 |
| H3K36me3 | ||||||
| Negative | 220 (47) | 1 (1.5) | 11 (19.6) | 6 (11.8) | 1 (7.7) | 0 (0) |
| Weak | 124 (26.5) | 3 (4.5) | 9 (16.1) | 11 (21.6) | 2 (15.4) | 2 (40) |
| Strong | 124 (26.5) | 62 (93.9) | 36 (64.3) | 34 (66.6) | 10 (76.9) | 3 (60) |
| Total | 468 | 66 | 56 | 51 | 13 | 5 |