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. 2019 Jan 31;9:1077. doi: 10.1038/s41598-018-37572-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Distinctive metabolic phenotypes among different types of GBS variants and the healthy controls. (A) Score scatter plot based on multivariate statistical model by PLS-DA. HC: healthy control. (B) Random permutation plot (999 times) on the datasets of the four groups. The vertical axis presents R² (blue points) and Q² (red points) values of the model. The horizontal axis shows the correlation coefficient between the original and the permuted Y-variable.