Table 2.
HIV-1 mediated upregulation of different interferon-stimulated genes (ISGs) in primary genital epithelial cells (GECs)
| Name | Gene | Microarray (fold changes a) | Real-time PCR (fold changes a) | Regulation |
|---|---|---|---|---|
| MX1 | Myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 | 2.60 | 5.44 | Up |
| ISG15 | Interferon-stimulated gene 15 | 2.75 | 7.80 | Up |
| IFIT1 | Interferon-induced protein with tetratricopeptide repeats 1 | 3.82 | 8.37 | Up |
| IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | 2.59 | 2.87 | Up |
| IFI44L | Interferon-induced protein 44-like | 2.29 | 5.57 | Up |
| RSAD2 | Radical S-adenosylmethionine domain containing 2 | 2.82 | 7.95 | Up |
| OAS1 | 2'-5'-Oligoadenylate synthetase 1 | 2.80 | 3.47 | Up |
| OAS2 | 2'-5'-Oligoadenylate synthetase 1 | 4.12 | 23.82 | Up |
| OAS3 | 2'-5'-Oligoadenylate synthetase 3 | 2.39 | 10.80 | Up |
| BST2 | Bone marrow stromal cell antigen 2 | 2.46 | 6.90 | Up |
aFold change values in HIV-1-exposed GECs compared with unexposed control.