Table 2.
Characteristics of the Population Studied for Outcomes of Mycoplasma genitalium Treatment
| Characteristic | Macrolide Susceptible (n = 77) |
Macrolide Resistant (n = 167) | Total (N = 244) |
|---|---|---|---|
| Time to test of curea, d, median (IQR) | 29 (25–41) | 27 (22–32) | 28 (22–35) |
| Age, y, median (IQR) | 26.0 (22.9–30.9) | 28.7 (25.6–34.4) | 27.9 (24.5–33.0) |
| Sex/sexualityb | |||
| Female | 29 (37.7) | 23 (13.8) | 52 (21.3) |
| Male, heterosexual | 32 (41.6) | 36 (21.6) | 68 (27.9) |
| MSM | 16 (20.8) | 108 (64.7) | 124 (50.8) |
| Site of detectionc | |||
| Cervix/vagina | 24 (31.1) | 21 (12.6) | 45 (18.4) |
| Urine | 49 (63.6) | 105 (62.9) | 154 (63.1) |
| Rectumd | 4 (5.2) | 41 (24.6) | 45 (18.4) |
| HIV serostatus | |||
| Negative | 62 (80.5) | 141 (84.4) | 203 (83.2) |
| Untested | 15 (19.5) | 10 (6.0) | 25 (10.3) |
| Positive | 0 | 16 (9.58) | 16 (6.56) |
| Asymptomaticc | 18 (23.4) | 43 (25.8) | 61 (25.0) |
| Symptomatic | 59 (76.6) | 124 (74.3) | 183 (75.0) |
| Clinical diagnosis | |||
| Nongonococcal urethritis | 31 (40.3) | 78 (46.7) | 109 (44.7) |
| Contact of Mycoplasma genitalium | 21 (27.3) | 38 (22.8) | 59 (24.2) |
| Othere | 5 (6.5) | 28 (16.8) | 33 (13.5) |
| Vaginal discharge/bleeding | 13 (16.9) | 7 (4.2) | 20 (8.2) |
| Proctitis | 3 (3.9) | 12 (7.2) | 15 (6.2) |
| Cervicitis/PID | 4 (5.2) | 4 (2.4) | 8 (3.3) |
Data are presented as No. (%) unless otherwise indicated.
Abbreviations: HIV, human immunodeficiency virus; IQR, interquartile range; MSM, men who have sex with men; PID, pelvic inflammatory disease.
aTime to test of cure defined as days from the start of the second (resistance-guided) antibiotic.
bFemale includes 5 women who have sex with women. MSM includes 3 transgender women.
cNo. and proportion with macrolide-resistance mutations were: urine, 105 (68.2%); rectum, 41 (91.1%); cervix/vagina, 21 (46.7%); asymptomatic, 43 (70.5%); symptomatic, 124 (67.8%).
dIncludes 4 multisite infections.
eOther diagnoses included contact of chlamydia or gonorrhea (n = 9), urethral gonorrhea (n = 3), pelvic pain not diagnosed as PID (n = 3), dyspareunia (n = 2), dysuria (n = 2), anal itch/discharge (n = 4), vaginal candidiasis (n = 3), bacterial vaginosis (n = 2), balanitis (n = 2), pain with defecation (n = 2), epididymitis (n = 2).