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. 2018 Dec 25;39:575–590. doi: 10.1016/j.ebiom.2018.12.036

Fig. 6.

Fig. 6

AKBA Alters Gene Expression by Decreasing H3K27me3. (A) Concentration dependent effects of AKBA on histone methylation. (B) Dynamics of histone methylation in presence of 20 μM AKBA. Representative of three independent experiments is shown in (A) and (B). (C) Changes in H3K27me3 ChIP-Seq signals with corresponding changes in gene expression from RNA-seq for psoriasis related genes.