Table 3.
Summary of the results of the hierarchical regression models testing for the effects of genetic and lifestyle risk variables on fornix and hippocampus mediator variables.
| Outcome variables | Adjusted R2 | Predictors in final regression model |
|---|---|---|
| Fornix MPF | 0.24 (p < 0.001) | Age (p < 0.001) |
| WHR (p = 0.02) | ||
| Fornix R1 | 0.28 (p < 0.001) | Age (p < 0.001) |
| ICV (p = 0.009) | ||
| Alcohol (p = 0.01) | ||
| WHR (p = 0.018) | ||
| Fornix kf | 0.23 (p < 0.001) | Age (p < 0.001) |
| WHR (p = 0.04) | ||
| Fornix ISOSF | 0.32 (p < 0.001) | Age (p < 0.001) |
| ICV (p = 0.03) | ||
| Sex (p = 0.001) | ||
| Right hippocampal ISOSF | 0.36 (p < 0.001) | Age (p < 0.001) |
| ICV (p = 0.008) | ||
| Sex (p = 0.002) | ||
| Diastolic BP (p = 0.035) | ||
| FH (p = 0.04) |
5% FDR corrected p-values are highlighted in bolds.