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. 2019 Jan 22;21:101686. doi: 10.1016/j.nicl.2019.101686

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© 2019 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Fig. 3 — Sickle-cell disease patients with chronic pain exhibit trending greater connectivity between the Locus Coeruleus and Dorsolateral Prefrontal Cortex compared with sickle-cell disease patients without chronic pain (t_(14.18) = 1.99, p = .06, d = 0.66).