Table 2. Neonatal outcomes of VLBWIs of KNN (2013–2016).
Variables | GA, wk | ||||||
---|---|---|---|---|---|---|---|
22–23 (n = 372) | 24–25 (n = 1,156) | 26–27 (n = 1,644) | 28–29 (n = 2,191) | 30–32 (n = 2,078) | > 32 (n = 828) | Total (n = 8,269) | |
Survival rate | 33 (28–38) | 65 (62–67) | 84 (82–85) | 94 (93–95) | 97 (96–98) | 98 (97–99) | 86 (85–87) |
RDS | 98 (95–99) | 98 (97–99) | 96 (95–97) | 89 (88–91) | 60 (58–62) | 21 (18–23) | 78 (77–79) |
BPD | 88 (80–93) | 64 (61–68) | 47 (44–49) | 26 (24–28) | 14 (13–16) | 5 (4–7) | 30 (29–31) |
ROP Tx. | 20 (16–25) | 25 (23–28) | 11 (9–12) | 3 (2–4) | 1 (0–1) | 0 (0–1) | 8 (7–8) |
NEC ≥ IIa | 20 (16–25) | 15 (13–17) | 9 (8–11) | 4 (3–5) | 3 (2–3) | 2 (1–4) | 7 (6–7) |
Sepsis | 38 (33–43) | 36 (33–39) | 31 (29–33) | 18 (16–19) | 11 (9–12) | 6 (4–8) | 21 (20–22) |
Drug for PDA | 39 (34–45) | 52 (49–55) | 48 (45–50) | 34 (32–36) | 21 (19–23) | 9 (7–11) | 34 (33–35) |
Ligation of PDA | 18 (14–23) | 25 (23–28) | 18 (16–20) | 7 (6–9) | 3 (3–4) | 2 (1–3) | 11 (10–12) |
IVH (≥ grade III) | 45 (39–51) | 27 (25–30) | 12 (11–14) | 5 (4–6) | 2 (1–3) | 1 (0–2) | 10 (9–10) |
PVL | 15 (11–20) | 12 (10–15) | 11 (9–12) | 8 (7–9) | 5 (4–6) | 2 (1–3) | 8 (7–9) |
Data are presented as percentage (range of probability: 95% confidence interval). There is a significant difference among groups if the probability ranges do not overlap with each other.
VLBWIs = very low birth weight infants, KNN = Korean Neonatal Network, GA = gestational age, RDS = respiratory distress syndrome, BPD = bronchopulmonary dysplasia, moderate to severe, ROP Tx. = therapy for retinopathy of prematurity before discharge from the neonatal intensive care unit, NEC = necrotizing enterocolitis, PDA = patent ductus arteriosus, IVH (≥ grade III) = grade III or more intraventricular hemorrhage, PVL = periventricular leukomalacia, cystic.