Table I. Gene Ontology terms enriched in proteins with the lowest T_ms (38.2–43.3^°C). MF = molecular function; BP = biological process; CC = cellular compartment. Shown are all terms with Fisher's p < 0.002. No multiple testing correction was applied as per the algorithm recommendations.

Category	Term	Annotated	Observed	Expected	Fisher's p
MF	structural constituent of ribosome	83	76	19.0	0.00E+00
MF	RNA binding	106	54	24.3	2.50E−06
MF	rRNA binding	7	7	1.6	3.20E−05
MF	nucleotide binding	390	122	89.4	1.10E−04
MF	GTP binding	16	11	3.7	1.10E−04
MF	structural constituent of cytoskeleton	6	6	1.4	1.40E−04
MF	nucleic acid binding	143	71	32.8	4.70E−04
MF	translation initiation factor activity	22	12	5.0	1.19E−03
BP	translation	172	113	40.0	0.00E+00
BP	RNA methylation	39	34	9.1	1.50E−17
BP	DNA-templated transcription, elongation	25	17	5.8	2.10E−06
BP	ribosome biogenesis	99	42	23.0	1.00E−04
BP	regulation of protein catabolic process	6	6	1.4	1.50E−04
BP	lignin biosynthetic process	15	10	3.5	4.00E−04
BP	DNA endoreduplication	9	7	2.1	8.10E−04
BP	cytoskeleton organization	66	27	15.4	8.40E−04
BP	embryo development ending in seed dorman …	91	34	21.2	1.29E−03
BP	translational initiation	17	10	4.0	1.64E−03
BP	pyrimidine ribonucleotide biosynthetic p …	37	17	8.6	1.78E−03
CC	cytosolic large ribosomal subunit	29	28	6.7	1.30E−17
CC	nucleolus	60	42	13.8	3.30E−15
CC	cytosolic small ribosomal subunit	20	19	4.6	7.90E−12
CC	proteasome regulatory particle, lid subc …	10	10	2.3	3.70E−07
CC	plastid small ribosomal subunit	9	9	2.1	1.60E−06
CC	plasmodesma	185	68	42.5	4.30E−06
CC	proteasome regulatory particle, base sub …	7	7	1.6	3.20E−05
CC	plastid large ribosomal subunit	8	7	1.8	2.10E−04
CC	nucleus	344	124	79.0	3.80E−04
CC	COPI vesicle coat	5	5	1.1	6.30E−04
CC	cytosol	619	190	142.1	7.30E−04
CC	ribonucleoprotein complex	126	87	28.9	8.20E−04
CC	ribosomal subunit	68	65	15.6	1.56E−03