Table II. Gene Ontology terms enriched in proteins with the highest T_ms (52.9–61.0^°C). MF = molecular function; BP = biological process; CC = cellular compartment. Shown are all terms with Fisher's p < 0.005. No multiple testing correction was applied as per the algorithm recommendations.

Category	Term	Annotated	Observed	Expected	Fisher's p
MF	Threonine-type endopeptidase activity	17	17	4.4	7.10E−11
MF	Hydrolase activity, hydrolyzing O-glycos …	54	25	13.9	6.80E−04
MF	Acid phosphatase activity	7	6	1.8	1.52E−03
MF	Electron transfer activity	29	15	7.4	2.16E−03
MF	Protein serine/threonine phosphatase act …	10	7	2.6	4.01E−03
MF	3-chloroallyl aldehyde dehydrogenase act …	10	7	2.6	4.01E−03
MF	Epoxide hydrolase activity	4	4	1.0	4.30E−03
BP	Protein refolding	7	7	1.8	6.50E−05
BP	Organic hydroxy compound catabolic proce …	4	4	1.0	4.10E−03
BP	Cell wall macromolecule catabolic proces …	4	4	1.0	4.10E−03
BP	Carbon fixation	12	10	3.0	4.70E−03
BP	Reductive pentose-phosphate cycle	6	5	1.5	4.90E−03
CC	Extracellular region	275	115	70.3	2.60E−11
CC	Proteasome core complex, alpha-subunit c …	10	10	2.6	1.10E−06
CC	Proteasome core complex	17	17	4.3	6.00E−05
CC	Vacuole	182	66	46.5	4.50E−04
CC	Plant-type cell wall	44	20	11.2	2.97E−03