Table II. Human subject information, histological diagnoses, and Helicobacter pylori status.

Subject	Case	Sample origina	Age	Sex	Histological diagnosisb	GC type	GC Histological Grade	TNM stage	Hp statusc
1	NQ3008	Colombia	75	M	NAG	UN	UN	UN	1
2	NQ3017	Colombia	61	M	MAG	UN	UN	UN	1
3	NQ3024	Colombia	66	F	NAG	UN	UN	UN	1
4	NQ3026	Colombia	78	F	MAG	UN	UN	UN	1
5	NQ3028	Colombia	55	M	NAG	UN	UN	UN	0
6	NQ3030	Colombia	56	M	IM	UN	UN	UN	0
7	NQ3037	Colombia	58	F	IM	UN	UN	UN	1
8	NQ3039	Colombia	74	F	IM	UN	UN	UN	0
9	NQ3043	Colombia	64	F	MAG	UN	UN	UN	1
10	NQ3067	Colombia	52	M	IM	UN	UN	UN	0
11	NQ3070	Colombia	54	F	IM	UN	UN	UN	0
12	NQ3082	Colombia	54	M	IM	UN	UN	UN	0
13	NQ3119	Colombia	79	F	NAG	UN	UN	UN	1
14	NQ3122	Colombia	66	F	NAG	UN	UN	UN	1
15	NQ3123	Colombia	57	F	MAG	UN	UN	UN	1
16	NQ3124	Colombia	54	M	NAG	UN	UN	UN	1
17	NQ3138	Colombia	64	F	NAG	UN	UN	UN	0
18	NQ3145	Colombia	53	M	MAG	UN	UN	UN	1
19	NQ3160	Colombia	62	F	IM	UN	UN	UN	0
20	NQ3166	Colombia	54	M	NAG	UN	UN	UN	1
21	NQ3168	Colombia	53	F	IM	UN	UN	UN	1
22	NQ3172	Colombia	66	M	MAG	UN	UN	UN	1
23	NQ3177	Colombia	73	M	IM	UN	UN	UN	1
24	NQ3184	Colombia	51	F	IM	UN	UN	UN	1
25	NQ3190	Colombia	77	M	IM	UN	UN	UN	0
26	NQ3201	Colombia	54	M	NAG	UN	UN	UN	1
27	NQ3270	Colombia	57	F	MAG	UN	UN	UN	1
28	NQ3327	Colombia	49	F	MAG	UN	UN	UN	1
29	NQ3380	Colombia	58	M	MAG	UN	UN	UN	1
30	NQ3396	Colombia	51	M	MAG	UN	UN	UN	1
31	95-0507	Chile	54	F	GC	Intestinal type	Moderately differentiated	II	UN
32	95-0753	Chile	68	M	GC	Intestinal type	Poorly differentiated	II	UN
33	95-1721	Chile	UN	UN	GC	Intestinal type	Moderately differentiated	UN	UN
34	95-2982	Chile	55	M	GC	Intestinal type	Poorly differentiated	IIIB	UN
35	95-4846	Chile	64	M	GC	Intestinal type	Poorly differentiated	IIIA	UN
36	95-5242	Chile	74	M	GC	Intestinal type	Moderately differentiated	II	UN
37	95-5501	Chile	74	M	GC	Intestinal type	Moderately differentiated	II	UN
38	95-5619	Chile	45	M	GC	Intestinal type	Moderately differentiated	IIIB	UN
39	95-5711	Chile	67	F	GC	Intestinal type	Moderately differentiated	IV	UN
40	95-6532	Chile	69	M	GC	Intestinal type	Well differentiated	IA	UN
41	95-6666	Chile	58	M	GC	Intestinal type	Poorly differentiated	IB	UN
42	95-7255	Chile	83	F	GC	Intestinal type	Poorly differentiated	IIIA	UN
43	95-1260	Chile	70	F	GC	Intestinal type	Poorly differentiated	II	UN
44	95-8565	Chile	70	M	GC	Intestinal type	Moderately differentiated	IA	UN
45	96-2083	Chile	60	M	GC	Intestinal type	Moderately differentiated	IB	UN

^a Colombian biopsies were harvested from high-risk gastric cancer patients during follow up endoscopy (24). Chilean samples were harvested during gastrectomy. UN = data unavailable.

^b Histological diagnosis represents the most advanced lesion reported and the area scored for IHC. NAG = non-atrophic gastritis; premalignant lesions included MAG = multifocal atrophic gastritis and IM = intestinal metaplasia; and GC = gastric cancer. Chilean subjects with GC did not receive chemotherapy or radiation therapy prior to gastrectomy.

^c Hp = H. pylori; 0 = Hp-negative, 1 = Hp-positive as determined by modified Steiner stain (24). All Colombian patients were positive at the time of initial enrollment. H. pylori culture was not performed on Chilean samples (UN = unavailable).