Table 2.
Effect of aqueous extract of Caralluma dalzielii on haematological parameters.
| Animal | Parameter | Dose (mg/kg) |
|||
|---|---|---|---|---|---|
| 150 | 300 | 600 | Control | ||
| WBC (x103/ul) | 8.30 ± 1.60 | 9.42 ± 0.95 | 10.24 ± 2.67 | 8.16 ± 1.92 | |
| LY (x103/ul) | 3.48 ± 1.00 | 4.48 ± 1.07* | 4.38 ± 0.68* | 2.16 ± 0.39 | |
| MO (x103/ul) | 1.20 ± 0.35 | 1.14 ± 0.14 | 1.00 ± 0.36 | 1.06 ± 0.37 | |
| GR (x103/ul) | 3.62 ± 1.43 | 3.88 ± 0.45 | 4.3 ± 2.23 | 4.94 ± 1.77 | |
| LY (%) | 45.9 ± 11.68 | 44.98 ± 7.54 | 54.14 ± 7.90 | 39.06 ± 13.82 | |
| Female | MO (%) | 13.14 ± 1.84 | 12.14 ± 1.66 | 8.88 ± 0.87 | 11.1 ± 2.30 |
| GR (%) | 40.96 ± 11.01 | 42.30 ± 6.29 | 36.62 ± 7.2 | 49.8 ± 11.98 | |
| RBC (x106/ul) | 6.26 ± 0.38 | 6.09 ± 0.25 | 5.93 ± 0.24 | 6.66 ± 0.62 | |
| Hgb (g/dl) | 13.8 ± 0.90 | 13.08 ± 0.63 | 12.94 ± 0.56 | 14.86 ± 1.40 | |
| HCT (%) | 43.36 ± 2.61 | 41.20 ± 1.56 | 40.9 ± 2.08 | 45.54 ± 3.49 | |
| MCV (fl) | 69.24 ± 0.48 | 68.22 ± 0.83 | 68.6 ± 1.16 | 68.92 ± 1.72 | |
| MCH (pg) | 21.98 ± 0.25 | 22.00 ± 0.18 | 21.6 ± 1.17 | 22.32 ± 0.47 | |
| MCHC (g/dl) | 31.74 ± 0.23 | 31.82 ± 0.35 | 31.46 ± 0.46 | 32.42 ± 0.64 | |
| RDW (%) | 14.18 ± 0.28 | 16.38 ± 0.62 | 15.62 ± 0.91 | 15.38 ± 0.56 | |
| PLT (x103/ul) | 531.00 ± 47.07 | 502.00 ± 83.20 | 512.2 ± 36.57 | 467.6 ± 43.13 | |
| PCT (%) | 0.48 ± 0.04 | 0.44 ± 0.07 | 0.47 ± 0.03 | 0.41 ± 0.04 | |
| MPV(fl) | 9.00 ± 0.15 | 8.86 ± 0.17 | 9.20 ± 0.10* | 8.74 ± 0.17 | |
| PDW (fl) | 14.46 ± 0.68 | 13.46 ± 0.65 | 14.16 ± 0.54 | 13.46 ± 0.46 | |
| WBC (x103/ul) | 8.60 ± 2.4 | 12.80 ± 3.29 | 12.10 ± 3.29 | 6.76 ± 0.87 | |
| LY (x103/ul) | 7.38 ± 1.96 | 9.10 ± 2.90* | 9.23 ± 1.87* | 5.14 ± 0.78 | |
| MO (x103/ul) | 0.18 ± 0.11 | 0.58 ± 0.17 | 0.40 ± 0.11 | 0.10 ± 0.03 | |
| GR (x103/ul) | 3.55 ± 0.52 | 3.17 ± 0.90 | 2.98 ± 0.32 | 3.10 ± 0.21 | |
| LY (%) | 86.36 ± 2.11 | 74.00 ± 5.16 | 71.40 ± 3.80 | 75.96 ± 4.84 | |
| Male | MO (%) | 2.24 ± 0.05 | 5.30 ± 1.72 | 4.63 ± 1.71 | 1.50 ± 0.32 |
| GR (%) | 41.23 ± 7.2 | 60.00 ± 3.33 | 58.13 ± 4.15 | 38.50 ± 4.66 | |
| RBC (x106/ul) | 7.7 ± 0.11 | 7.23 ± 0.38 | 7.15 ± 0.36 | 7.71 ± 0.21 | |
| Hgb (g/dl) | 14.58 ± 0.35 | 13.40 ± 0.57 | 13.28 ± 0.49 | 14.50 ± 0.13 | |
| HCT (%) | 42.38 ± 1.57 | 38.64 ± 2.91 | 38.10 ± 1.48 | 40.64 ± 0.51 | |
| MCV (fl) | 53.74 ± 1.52 | 51.78 ± 1.24 | 53.63 ± 1.31 | 52.88 ± 1.04 | |
| MCH (pg) | 19.04 ± 0.5 | 18.62 ± 0.72 | 18.63 ± 0.53 | 18.76 ± 0.30 | |
| MCHC (g/dl) | 35.44 ± 0.11 | 34.98 ± 0.14 | 34.70 ± 0.10 | 35.62 ± 0.35 | |
| RDW (%) | 17.36 ± 0.18 | 18.48 ± 0.29 | 17.70 ± 0.45 | 16.86 ± 0.68 | |
| PLT (x103/ul) | 598 ± 54.72 | 674.80 ± 41.29 | 691.50 ± 71.71 | 737.20 ± 58.02 | |
| PCT (%) | 0.44 ± 0.04 | 0.48 ± 0.07 | 0.41 ± 0.13 | 0.50 ± 0.04 | |
| MPV(fl) | 7.16 ± 0.07 | 4.78 ± 1.79 | 7.85 ± 0.69* | 3.04 ± 1.64 | |
| PDW (fl) | 17.52 ± 1.89 | 20.80 ± 4.50 | 22.53 ± 7.22 | 16.18 ± 0.90 | |
Values are presented as Mean ± S.E.M, n = 6; Significant in relation to control at *p < 0.05, One-way ANOVA followed by Dunnett's post hoc test.