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. 2019 Jan 29;5(1):e01179. doi: 10.1016/j.heliyon.2019.e01179

Table 3.

Effect of aqueous extract of Caralluma dalzielii on biochemical parameters.

Animal Parameter Dose (mg/kg)
150 300 600 control
U (mmol/l) 7.30 ± 0.86* 4.66 ± 0.35 5.73 ± 0.71 4.96 ± 0.27
Cr (mg/dl) 0.7 ± 0.00 0.7 ± 0.00 0.7 ± 0.00 0.7 ± 0.00
Na+ (mmol) 138 ± 2.8 134.8 ± 0.73 133 ± 3.01 138.4 ± 2.34
K+ (mmol) 4.5 ± 0.32 3.96 ± 0.21 4.03 ± 0.31 3.8 ± 0.14
Female Cl (mmol) 95.3 ± 2.07 89.8 ± 1.56* 95.00 ± 1.91 97.2 ± 1.36
HCO3- (mmol) 21.67 ± 0.52 23.6 ± 1.51 24.00 ± 1.08 23.2 ± 0.66
Total Protein (g/dl) 6.33 ± 0.07 6.68 ± 0.18 6.43 ± 0.17 6.12 ± 0.44
Albumin (g/dl) 3.00 ± 0.04 2.84 ± 0.11 2.80 ± 0.09 2.66 ± 0.19
AST (U/L) 177.33 ± 5.47 169.6 ± 17.46 188.25 ± 3.90 194.2 ± 5.44
ALT (U/L) 54.0 ± 10.11 47.4 ± 1.94 67 ± 3.61* 49.4 ± 1.78
T. Bilirubin (mg/dl) 0.45 ± 0.11 1.156 ± 0.51 0.73 ± 0.05 0.582 ± 1.55
D. Bilirubin (mg/dl) 0.10 ± 0.02 0.184 ± 0.06 0.20 ± 0.02* 0.112 ± 0.03



U (mmol/l) 3.44 ± 0.54 4.90 ± 0.06* 3.53 ± 0.75 2.80 ± 0.26
Cr (mg/dl) 0.82 ± 0.05 0.78 ± 0.05 0.85 ± 0.10 0.66 ± 0.06
Na+ (mmol) 142.60 ± 0.87 142.00 ± 0.55 143.75 ± 0.85 144.40 ± 1.07
K+ (mmol) 5.00 ± 0.03 5.00 ± 0.10 4.55 ± 0.26 5.00 ± 0.05
Male Cl (mmol) 101.80 ± 0.92 102.50 ± 1.17 102.50 ± 1.44 105.80 ± 1.53
HCO3- (mmol) 25.00 ± 1.52 24.20 ± 0.86* 26.00 ± 1.47 27.00 ± 0.84
Total Protein (g/dl) 5.80 ± 0.11 5.78 ± 0.17 5.63 ± 0.23 6.06 ± 0.24
Albumin (g/dl) 3.12 ± 0.19 3.22 ± 0.07 3.00 ± 0.17 3.20 ± 0.12
AST (U/L) 235.20 ± 6.66* 238.40 ± 18.43 257.75 ± 12.48* 203.00 ± 10.41
ALT (U/L) 65.40 ± 19.26 68.40 ± 3.23 117.56 ± 11.26* 79.60 ± 5.49
T. Bilirubin (mg/dl) 0.33 ± 0.08 0.76 ± 0.22 0.78 ± 0.20 0.50 ± 0.12
D. Bilirubin (mg/dl) 0.09 ± 0.03 0.11 ± 0.02 0.08 ± 0.02 0.10 ± 0.02

Data presented as Mean ± S.E.M. *p < 0.05; U= Urea, Cr= Creatinine, aspartate aminotransferase (AST), alanine amino transferase (ALT), T. = Total, C. = Conjugated, D. = Direct.